Modelling the p53 gene regulatory network

p53 is the central protein in the DNA damage response and is part of a complex and extensive gene regulatory network. This network integrates a variety of stress signals to produce the up-regulation of active p53 and a range of effects including apoptosis, growth arrest and DNA damage repair. The p5...

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Bibliographic Details
Main Author: Brewer, Daniel Simon
Published: University College London (University of London) 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.427958