Analysis of DNA damage and cellular responses to platinum-based chemotherapeutic agents in 'in vitro' models of non-small cell lung cancer
Response to cisplatin was investigated in a panel of NSCLC cell lines in terms of sensitivity/resistance to this agent, DNA crosslink formation and repair, cell cycle effects, apoptosis and gene expression changes. Measures of survival revealed a differential response between cell lines. The level o...
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University of Leicester
2005
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.424031 |