Evolution of drug resistance in Mycobacterium tuberculosis

This thesis examines the contrasting roles of genetic drift and selection on the emergence of drug resistance in Mycobacterium tuberculosis . In clinical practice some alleles of rifampicin resistance are isolated more frequently than others. To identify if this variation is due to genetic drift or...

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Bibliographic Details
Main Author: Billington, Owen James
Published: University College London (University of London) 2005
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.420964