The adaptation of the Cre-loxP gene disruption system for use in Candida albicans

At the start of this project, the systems available for gene disruption in <i>C. albicans</i> were laborious and inefficient.  Both alleles of a target locus need to be inactivated to construct a homozygous null mutant in this diploid fungus.  This often requires the recycling of transfo...

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Bibliographic Details
Main Author: Dennison, Paul Mark John
Published: University of Aberdeen 2004
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.415547