An investigation of mechanisms responsible for modulated biosynthetic function in 3-dimensional cultures of a human hepatocyte cell line, for potential use in a bioartificial liver support system
The thesis describes the performance of the HepG2 cell line, a proliferating liver cell line, potentially to be used as the cellular component of a bioartificial liver (BAL). HepG2 cells in 3-Dimensional (3-D) spheroidal culture demonstrate dramatically improved function, compared to monolayer cultu...
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University College London (University of London)
2004
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.414777 |