A study of synthetic routes to pyridine-stretched nucleoside analogues

An introduction to the use of oligonucleotides as antigene or antisense therapeutic agents is presented. This includes an analysis of the major areas of structural change implemented to improve the stability, specificity, nuclease resistance and cellular delivery of oligonucleotides. The synthetic a...

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Bibliographic Details
Main Author: Crawford, Julia Ann
Published: Keele University 2004
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.414756