An ultrastructural and molecular analysis of neuronal degeneration in Huntington's disease

Huntington's disease (HD) is an inherited, progressive, neurodegenerative disorder for which there is no effective treatment. It is one of nine disorders known to be caused by the expansion of a genomic CAG repeat sequence, producing a protein with an expanded array of polyglutamine residues. T...

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Bibliographic Details
Main Author: Bannister, Lee-Jay
Published: University College London (University of London) 2004
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.413668