Development and characterisation of 3D skeletal muscle constructs under defined mechanical regulation
It has been shown that the IGF-I gene is spliced in response to mechanical signals producing forms of IGF-I which have different actions. To study the roles of environmental mechanical cues on gene programming and splicing in developing muscle, an in vitro 3D cell culture system was employed. C2C12...
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University College London (University of London)
2005
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.413380 |