Design and cancer-targeting potential of antibody-based molecules directed against carcinoembryonic antigen

This thesis examines the use of protein engineering to create antibody-based molecules for cancer treatment. The targeting unit used for these molecules was the single chain Fv antibody fragment MFE-23, which is directed against the tumour-associated marker carcinoembryonic antigen (CEA). It was hyp...

Full description

Bibliographic Details
Main Author: Huhalov, Alexandra
Published: University College London (University of London) 2004
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.412570