Expression and regulation of cytochrome P450 3As in human hepatocytes

Cytochrome P450 3A represents the most abundant P450 subfamily in human liver, and is responsible for the metabolism of >50 % of drugs on the market today. An area of intense study has been the xenobiotic regulation of CYP3A gene expression: this phenomenon potentially leads to altered pharmacoki...

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Bibliographic Details
Main Author: Phillips, Anna Louise
Published: University of Surrey 2004
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.412044