An investigation of the transcriptional regulation of thiamin biosynthesis in Saccharomyces cerevisiae

Baker's yeast Saccharomyces cerevisiae can synthesise vitamin B1, thiamin, de nova. Exogenously supplied vitamin is, however, taken up very efficiently, leading to high intracellular levels of the enzyme cofactor thiamin diphosphate (ThDP) and subsequent repression of genes encoding the biosynt...

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Bibliographic Details
Main Author: Savill, Stuart
Published: University of Leicester 2004
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.411576