The leukaemogenic fusion protein MOZ-TIF2 inhibits nuclear receptor-mediated transcription and mislocalises CBP
Chromosomal rearrangements associated with the M4/M5 subtype of Acute Myeloid Leukaemia include fusions of the gene encoding the histone acetyltransferase (HAT) MOZ with genes encoding the transcription factor coactivators TIF2, CBP or p300. The physiological roles of MOZ in vivo remain to be establ...
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University of Leicester
2003
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.409989 |