The role of thrombin and protease activated receptor-1 in the pathogenesis of pulmonary fibrosis

Pulmonary fibrosis is characterised by excessive deposition of extracellular matrix proteins within the lung parenchyma. Activation of the coagulation cascade occurs in this condition and thrombin levels are increased in bronchoalveolar lavage fluid (BALF) from patients with this disorder. In additi...

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Bibliographic Details
Main Author: Howell, David Christopher John
Published: University College London (University of London) 2004
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.408068