Cyclic imine sugars : towards the synthesis of transition-state mimics as potential glycosyltransferase inhibitors
This thesis describes the development of methodology for the synthesis of cyclic imine-sugars, and their use in the synthesis of aza-sugars as potential sugar-processing enzyme inhibitors. Our goals include the synthesis of cyclic imines of L-rhamnose, D-glucose, and L-idose stereochemistry, and the...
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Durham University
2003
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.402206 |