Synthetic and enzymatic studies related to branched-chain amino acid metabolism

Several sytheses of a-acetolactate analogues (2-hydroxy-3-oxo carboxylic esters) and related compounds were developed. The action of the enzyme acetolactate decarboxylase upon these compounds was studied. A synthesis of 3-bromo-2-oxo carboxylic acids, esters and amides was developed. Inhibition stud...

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Bibliographic Details
Main Author: Rathbone, Daniel Lee
Published: University of Warwick 1987
Subjects:
547
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.383329