Asymmetric reduction using enzymes and chiral chemical reagents
This thesis is concerned with the asymmetric reduction of achiral substrates to chiral products on a preparative scale. In the first case dihydrofolate reductase was used to catalyse the conversion of 7,8-dihydrofolic acid into (6S)- 5,6,7, B-tetrahydrofolic acid. The required coenzyme,NADPH, was re...
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University of Strathclyde
1984
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.371116 |