Applications of tritium and oxygen-17 labelled molecules for the study of molecular interactions

This thesis details three different projects. The first project describes the synthesis of tritium-labelled Dickerson's DNA dodecamer, 5'-CGCGAATTCGCG-3', using phosphite triester chemistry. Coupling of the or A5 or A6 2'-deoxyadenosine nucleosides was optimized with only five mo...

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Bibliographic Details
Main Author: Culf, Adrian Shaun
Published: University of Surrey 1994
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359925