The effect of genotoxic compounds on the fidelity of DNA synthesis

The fidelity with which DNA polymerases replicate the synthetic polynucleotide polydA. oligodT, can be determined in vitro by measuring the ratio of incorporation of non-complementary nucleotides and complementary nucleotides into polymeric material. In order to study the effect of in vivo or in vit...

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Bibliographic Details
Main Author: Power, Christine Anna Grek
Published: University of Surrey 1983
Subjects:
572
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.344402