Exploiting the retrograde transport of disarmed toxins for the delivery of exogenous antigens into MHC class 1 presentation pathway

The targeting of exogenous antigen into the MHC class 1-restricted presentation pathway is required for the induction of cytotoxic T lymphocytes (CTL) which have been shown to be an important component of the protective response to intracellular antigens and also induce immunity to tumour cells. Thu...

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Bibliographic Details
Main Author: Noakes, Karen
Published: University of Warwick 1999
Subjects:
579
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342601