An investigation into the neuropharmacology and toxicology of some novel analogues of Tacrine
A series of novel 9-amino-1,2,3,4-tetrahydroacridine compounds with alkyl substituents in the saturated ring were synthesized. The selected lead compound was 2-t-butyl-9-amino- 1,2,3,4-tetrahydroacridine (2tBuTHA), which in preliminary studies demonstrated a potent inhibition of acetylcholinesterase...
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University of Hertfordshire
1995
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283891 |