Effects of alteration in liver blood flow and in hepatic enzyme induction on the pharmacokinetics of lignocaine and tocainide
The investigation was undertaken to observe the effects of alteration of liver blood flow and of liver metabolism on the kinetics of two antiarrhythmic drugs, lignocaine, a highly hepatic cleared drug and tocainide, a drug with low hepatic clearance in intact rats. An initial study was undertaken to...
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University of Bath
1980
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.280987 |