Transcriptional targeting of lentiviral vectors to the erythroblastic progeny of hematopoietic stem cells
Correction of blood genetic disorders requires permanent gene transfer into self renewing, hematopoietic stem cells (HSC), and regulation of transgene expression in specific cell lineages. HIV-derived lentiviral vectors are very effective in transducing rare, non-dividing stem cell populations witho...
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Open University
2003
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Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275107 |