The role of phosphodiesterase 3, phosphodiesterase 5, and the inhibitory γ subunit of the retinal cyclic GMP phosphodiesterase, in pulmonary hypertension

Chronic treatment of rats (to induce pulmonary hypertension, PHT) for 14 days increased cGMP-inhibited. cAMP specific phosphodiesterase (PDE3), and cGMP binding, cGMP specific phosphodiesterase (PDE5) activities in selected branches of the pulmonary artery (MacLean et al., 1997). The objective of th...

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Bibliographic Details
Main Author: Murray, Fiona
Published: University of Glasgow 2003
Subjects:
616
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270998