The cytotoxicity of the non-steroidal anti-inflammatory drugs in human colorectal cancer cells in vitro : a role for the polyamines?

The non-steroidal anti-inflammatory drugs (NSAIDs) are known to have chemopreventative properties against colorectal cancer. Recent evidence suggests the mechanism of action is not through inhibition of cyclo-oxygenase (COX), as previously thought. We hypothesised that the NSAIDs could be acting thr...

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Bibliographic Details
Main Author: Hughes, Alun
Published: University of Aberdeen 2002
Subjects:
616
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.252109