Inhibition of Aryl Hydrocarbon Receptor (AhR) Activity Decreases ABCG2 Expression and Activity
The androgen receptor’s (AR) resurgence following treatment leads to castration resistant prostate cancer (CRPC). Studies show that the aryl hydrocarbon receptor (AhR) regulates AR signaling, is constitutively active, and enhances AR signaling in CRPC. AhR has ligands with carcinogenic properties an...
Main Author: | |
---|---|
Format: | Others |
Published: |
DigitalCommons@Robert W. Woodruff Library, Atlanta University Center
2018
|
Subjects: | |
Online Access: | http://digitalcommons.auctr.edu/cauetds/122 http://digitalcommons.auctr.edu/cgi/viewcontent.cgi?article=1212&context=cauetds |