Inhibition of Aryl Hydrocarbon Receptor (AhR) Activity Decreases ABCG2 Expression and Activity

The androgen receptor’s (AR) resurgence following treatment leads to castration resistant prostate cancer (CRPC). Studies show that the aryl hydrocarbon receptor (AhR) regulates AR signaling, is constitutively active, and enhances AR signaling in CRPC. AhR has ligands with carcinogenic properties an...

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Bibliographic Details
Main Author: Williams, Stanley J
Format: Others
Published: DigitalCommons@Robert W. Woodruff Library, Atlanta University Center 2018
Subjects:
Online Access:http://digitalcommons.auctr.edu/cauetds/122
http://digitalcommons.auctr.edu/cgi/viewcontent.cgi?article=1212&context=cauetds