Modeling Emergent Behaviors of Multi-Cellular Systems in 3D Extracellular Matrix: Heterogeneous Extracellular Matrix Reconstruction, Cell Micromechanics and Novel Mechanotaxis
abstract: Collective cell migration in the 3D fibrous extracellular matrix (ECM) is crucial to many physiological and pathological processes such as tissue regeneration, immune response and cancer progression. A migrating cell also generates active pulling forces, which are transmitted to the ECM fi...
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Format: | Doctoral Thesis |
Language: | English |
Published: |
2019
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Online Access: | http://hdl.handle.net/2286/R.I.53566 |