Modeling Emergent Behaviors of Multi-Cellular Systems in 3D Extracellular Matrix: Heterogeneous Extracellular Matrix Reconstruction, Cell Micromechanics and Novel Mechanotaxis

abstract: Collective cell migration in the 3D fibrous extracellular matrix (ECM) is crucial to many physiological and pathological processes such as tissue regeneration, immune response and cancer progression. A migrating cell also generates active pulling forces, which are transmitted to the ECM fi...

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Bibliographic Details
Other Authors: Nan, Hanqing (Author)
Format: Doctoral Thesis
Language:English
Published: 2019
Subjects:
Online Access:http://hdl.handle.net/2286/R.I.53566