Engineering PNIPAAm Biomaterial Scaffolds to Model Microenvironmental Regulation of Glioblastoma Stem-Like Cells

abstract: Following diagnosis of a glioblastoma (GBM) brain tumor, surgical resection, chemotherapy and radiation together yield a median patient survival of only 15 months. Importantly, standard treatments fail to address the dynamic regulation of the brain tumor microenvironment that actively supp...

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Bibliographic Details
Other Authors: Heffernan, John M. (Author)
Format: Doctoral Thesis
Language:English
Published: 2017
Subjects:
Online Access:http://hdl.handle.net/2286/R.I.46249