T-Cell Immunogenicity and Dysfunction in Cancer and Viral Diseases
abstract: CD8+ T-lymphocytes (CTLs) are central to the immunologic control of infections and are currently at the forefront of strategies that enhance immune based treatment of a variety of tumors. Effective T-cell based vaccines and immunotherapies fundamentally rely on the interaction of CTLs with...
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Format: | Doctoral Thesis |
Language: | English |
Published: |
2017
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Online Access: | http://hdl.handle.net/2286/R.I.46218 |