Solving the Mechanism of Na+/H+ Antiporters Using Molecular Dynamics Simulations
abstract: Na+/H+ antiporters are vital membrane proteins for cell homeostasis, transporting Na+ ions in exchange for H+ across the lipid bilayer. In humans, dysfunction of these transporters are implicated in hypertension, heart failure, epilepsy, and autism, making them well-established drug target...
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| Format: | Doctoral Thesis |
| Language: | English |
| Published: |
2016
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| Online Access: | http://hdl.handle.net/2286/R.I.40833 |