Time-Dependent Models of Signal Transduction Networks
abstract: Signaling cascades transduce signals received on the cell membrane to the nucleus. While noise filtering, ultra-sensitive switches, and signal amplification have all been shown to be features of such signaling cascades, it is not understood why cascades typically show three or four layers....
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Format: | Doctoral Thesis |
Language: | English |
Published: |
2013
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Online Access: | http://hdl.handle.net/2286/R.I.20992 |