Multifaceted regulation of V(D)J recombination

Multifaceted regulation of V(D)J recombination

abstract: V(D)J recombination is responsible for generating an enormous repertoire of immunoglobulins and T cell receptors, therefore it is a centerpiece to the formation of the adaptive immune system. The V(D)J recombination process proceeds through two steps, site-specific cleavage at RSS (Recombi...

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Bibliographic Details
Other Authors: Wang, Guannan (Author)
Format: Doctoral Thesis
Language:English
Published: 2012
Subjects:
Biochemistry
Molecular biology
Molecular physics
coding end retention
interaction
RAG
RSS
signal end retention
stability
Online Access:http://hdl.handle.net/2286/R.I.14681

Internet

http://hdl.handle.net/2286/R.I.14681

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