miR-9a mediates the role of Lethal giant larvae as an epithelial growth inhibitor in Drosophila

miR-9a mediates the role of Lethal giant larvae as an epithelial growth inhibitor in Drosophila

Drosophila lethal giant larvae (lgl) encodes a conserved tumor suppressor with established roles in cell polarity, asymmetric division, and proliferation control. Lgl's human orthologs, HUGL1 and HUGL2, are altered in human cancers, however, its mechanistic role as a tumor suppressor remains po...

Full description

Bibliographic Details
Main Authors: Daniel, Scott G., Russ, Atlantis D., Guthridge, Kathryn M., Raina, Ammad I., Estes, Patricia S., Parsons, Linda M., Richardson, Helena E., Schroeder, Joyce A., Zarnescu, Daniela C.
Other Authors: Univ Arizona, Dept Mol & Cellular Biol
Language:en
Published: COMPANY OF BIOLOGISTS LTD 2018
Subjects:
miRNA
Epithelial growth
Drosophila
Online Access:http://hdl.handle.net/10150/627079
http://arizona.openrepository.com/arizona/handle/10150/627079

Internet

http://hdl.handle.net/10150/627079
http://arizona.openrepository.com/arizona/handle/10150/627079

Similar Items