Exploring the Molecular Mechanisms by which AID Recombinase Interacts with DNA Secondary Structures involved in Cancer
Genomic complexity in non-Hodgkin’s Diffuse Large B-cell Lymphoma (DLBCL) leads to a treatment failure in ~40% of patients. Activation-Induced Cytosine Deaminase (AID), one of the enzymes involved in generating antibody diversity via class switching recombination (CSR) and somatic hypermutation (...
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| Language: | en_US |
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The University of Arizona.
2017
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| Online Access: | http://hdl.handle.net/10150/626339 http://arizona.openrepository.com/arizona/handle/10150/626339 |