Functional Changes in the Gut Microbiome Contribute to Transforming Growth Factor β-Deficient Colon Cancer
Colorectal cancer (CRC) is one of the most treatable cancers, with a 5-year survival rate of similar to 64%, yet over 50,000 deaths occur yearly in the United States. In 15% of cases, deficiency in mismatch repair leads to null mutations in transforming growth factor beta (TGF-beta) type II receptor...
Main Authors: | Daniel, Scott G., Ball, Corbie L., Besselsen, David G., Doetschman, Tom, Hurwitz, Bonnie L. |
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Other Authors: | Univ Arizona, Dept Mol & Cellular Biol |
Language: | en |
Published: |
AMER SOC MICROBIOLOGY
2017
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Subjects: | |
Online Access: | http://hdl.handle.net/10150/626089 http://arizona.openrepository.com/arizona/handle/10150/626089 |
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