Functional Changes in the Gut Microbiome Contribute to Transforming Growth Factor β-Deficient Colon Cancer

Functional Changes in the Gut Microbiome Contribute to Transforming Growth Factor β-Deficient Colon Cancer

Colorectal cancer (CRC) is one of the most treatable cancers, with a 5-year survival rate of similar to 64%, yet over 50,000 deaths occur yearly in the United States. In 15% of cases, deficiency in mismatch repair leads to null mutations in transforming growth factor beta (TGF-beta) type II receptor...

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Bibliographic Details
Main Authors: Daniel, Scott G., Ball, Corbie L., Besselsen, David G., Doetschman, Tom, Hurwitz, Bonnie L.
Other Authors: Univ Arizona, Dept Mol & Cellular Biol
Language:en
Published: AMER SOC MICROBIOLOGY 2017
Subjects:
Helicobacter hepaticus
Smad3
bioinformatics
butyrate
colon cancer
gut inflammation
gut microbiome
host-pathogen interactions
metagenomics
metatranscriptomics
polyamines
Online Access:http://hdl.handle.net/10150/626089
http://arizona.openrepository.com/arizona/handle/10150/626089

Internet

http://hdl.handle.net/10150/626089
http://arizona.openrepository.com/arizona/handle/10150/626089

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