The impact of age and gut microbiota on Th17 and Tfh cells in K/BxN autoimmune arthritis

Background: Age is an important risk factor for rheumatoid arthritis (RA), which often develops in middle age. However, how age-associated changes in immunity impact RA is poorly understood. Gut microbiota are known to be involved in the pathogenesis of RA, but the effects of microbiota in older sub...

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Bibliographic Details
Main Authors: Teng, Fei, Felix, Krysta M., Bradley, C. Pierce, Naskar, Debdut, Ma, Heqing, Raslan, Walid A., Wu, Hsin-Jung Joyce
Other Authors: Univ Arizona, Dept Immunobiol
Language:en
Published: BIOMED CENTRAL LTD 2017
Subjects:
Age
Tfh
Online Access:http://hdl.handle.net/10150/625527
http://arizona.openrepository.com/arizona/handle/10150/625527