Protein kinase A regulates the Ras, Rap1 and TORC2 pathways in response to the chemoattractant cAMP in Dictyostelium

Protein kinase A regulates the Ras, Rap1 and TORC2 pathways in response to the chemoattractant cAMP in Dictyostelium

Efficient directed migration requires tight regulation of chemoattractant signal transduction pathways in both space and time, but the mechanisms involved in such regulation are not well understood. Here, we investigated the role of protein kinase A (PKA) in controlling signaling of the chemoattract...

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Bibliographic Details
Main Authors: Scavello, Margarethakay, Petlick, Alexandra R., Ramesh, Ramya, Thompson, Valery F., Lotfi, Pouya, Charest, Pascale G.
Other Authors: Univ Arizona, Dept Chem & Biochem
Language:en
Published: COMPANY OF BIOLOGISTS LTD 2017
Subjects:
Chemotaxis
Migration
PKA
Negative feedback
Directional sensing
Chemotactic signaling
Online Access:http://hdl.handle.net/10150/624638
http://arizona.openrepository.com/arizona/handle/10150/624638

Internet

http://hdl.handle.net/10150/624638
http://arizona.openrepository.com/arizona/handle/10150/624638

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