Translocation of the papillomavirus L2/vDNA complex across the limiting membrane requires the onset of mitosis

The human papillomavirus type 16 (HPV16) L2 protein acts as a chaperone to ensure that the viral genome (vDNA) traffics from endosomes to the trans-Golgi network (TGN) and eventually the nucleus, where HPV replication occurs. En route to the nucleus, the L2/vDNA complex must translocate across limit...

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Bibliographic Details
Main Authors: Calton, Christine M., Bronnimann, Matthew P., Manson, Ariana R., Li, Shuaizhi, Chapman, Janice A., Suarez-Berumen, Marcela, Williamson, Tatum R., Molugu, Sudheer K., Bernal, Ricardo A., Campos, Samuel K.
Other Authors: Univ Arizona, Canc Biol Grad Interdisciplinary Program
Language:en
Published: PUBLIC LIBRARY SCIENCE 2017
Online Access:http://hdl.handle.net/10150/624634
http://arizona.openrepository.com/arizona/handle/10150/624634