Development of Orthogonal Split-Kinase and Split-Phosphatase Systems for Interrogating and Rewiring Signal Transduction

The function of most proteins is regulated by post-translational modifications, of which phosphorylation in particular has been shown to be ubiquitous and of paramount importance to cell signaling. Two enzyme families, protein kinases and phosphatases, regulate phosphorylation, and aberrant activiti...

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Bibliographic Details
Main Author: Castillo-Montoya, Javier
Other Authors: Ghosh, Indraneel
Language:en_US
Published: The University of Arizona. 2016
Subjects:
Online Access:http://hdl.handle.net/10150/623179
http://arizona.openrepository.com/arizona/handle/10150/623179