Development of Orthogonal Split-Kinase and Split-Phosphatase Systems for Interrogating and Rewiring Signal Transduction
The function of most proteins is regulated by post-translational modifications, of which phosphorylation in particular has been shown to be ubiquitous and of paramount importance to cell signaling. Two enzyme families, protein kinases and phosphatases, regulate phosphorylation, and aberrant activiti...
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Language: | en_US |
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The University of Arizona.
2016
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Online Access: | http://hdl.handle.net/10150/623179 http://arizona.openrepository.com/arizona/handle/10150/623179 |