Defining Mechanisms of Sensitivity and Resistance to Histone Deacetylase Inhibitors to Develop Effective Thereaputic Strategies for the Treatment of Aggressive Diffuse Large B-Cell Lymphoma

Diffuse large B-cell lymphoma (DLBCL) is the most common form of non-Hodgkin lymphoma (NHL). The current standard of care is the combination of rituximab with cyclophosphamide, doxorubicin, vincristine and prednisone (R-CHOP), but this only results in a 60% over-all 5-year survival rate, thus highli...

Full description

Bibliographic Details
Main Author: Havas, Aaron Paul
Other Authors: Smith, Catharine L.
Language:en_US
Published: The University of Arizona. 2016
Subjects:
Online Access:http://hdl.handle.net/10150/622977
http://arizona.openrepository.com/arizona/handle/10150/622977