Llgl1 prevents metaplastic survival driven by epidermal growth factor dependent migration

Llgl1 prevents metaplastic survival driven by epidermal growth factor dependent migration

We have previously demonstrated that Llgl1 loss results in a gain of mesenchymal phenotypes and a loss of apicobasal and planar polarity. We now demonstrate that these changes represent a fundamental shift in cellular phenotype. Llgl1 regulates the expression of multiple cell identity markers, inclu...

Full description

Bibliographic Details
Main Authors: Greenwood, Erin, Maisel, Sabrina, Ebertz, David, Russ, Atlantis, Pandey, Ritu, Schroeder, Joyce
Other Authors: Univ Arizona, Dept Mol & Cellular Biol
Language:en
Published: IMPACT JOURNALS LLC 2016
Subjects:
polarity
migration
Llgl1
epidermal growth factor receptor
TAZ
Online Access:http://hdl.handle.net/10150/622116
http://arizona.openrepository.com/arizona/handle/10150/622116

Internet

http://hdl.handle.net/10150/622116
http://arizona.openrepository.com/arizona/handle/10150/622116

Similar Items