Control of translational activation by PIM kinase in activated B-cell diffuse large B-cell lymphoma confers sensitivity to inhibition by PIM447
The PIM family kinases promote growth and survival of tumor cells and are expressed in a wide variety of human cancers. Their potential as therapeutic targets, however, is complicated by overlapping activities with multiple other pathways and remains poorly defined in most clinical scenarios. Here w...
Main Authors: | Peters, Tara L., Li, Lingxiao, Tula-Sanchez, Ana A., Pongtornpipat, Praechompoo, Schatz, Jonathan H. |
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Other Authors: | Univ Arizona, Dept Mol & Cellular Biol |
Language: | en |
Published: |
IMPACT JOURNALS LLC
2016
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Subjects: | |
Online Access: | http://hdl.handle.net/10150/622115 http://arizona.openrepository.com/arizona/handle/10150/622115 |
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