Control of translational activation by PIM kinase in activated B-cell diffuse large B-cell lymphoma confers sensitivity to inhibition by PIM447

The PIM family kinases promote growth and survival of tumor cells and are expressed in a wide variety of human cancers. Their potential as therapeutic targets, however, is complicated by overlapping activities with multiple other pathways and remains poorly defined in most clinical scenarios. Here w...

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Bibliographic Details
Main Authors: Peters, Tara L., Li, Lingxiao, Tula-Sanchez, Ana A., Pongtornpipat, Praechompoo, Schatz, Jonathan H.
Other Authors: Univ Arizona, Dept Mol & Cellular Biol
Language:en
Published: IMPACT JOURNALS LLC 2016
Subjects:
Online Access:http://hdl.handle.net/10150/622115
http://arizona.openrepository.com/arizona/handle/10150/622115