Regulation of Thrombin-Induced Lung Endothelial Cell Barrier Disruption by Protein Kinase C Delta

Protein Kinase C (PKC) plays a significant role in thrombin-induced loss of endothelial cell (EC) barrier integrity; however, the existence of more than 10 isozymes of PKC and tissue-specific isoform expression has limited our understanding of this important second messenger in vascular homeostasis....

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Bibliographic Details
Main Authors: Xie, Lishi, Chiang, Eddie T., Wu, Xiaomin, Kelly, Gabriel T., Kanteti, Prasad, Singleton, Patrick A., Camp, Sara M., Zhou, Tingting, Dudek, Steven M., Natarajan, Viswanathan, Wang, Ting, Black, Steven M., Garcia, Joe G. N., Jacobson, Jeffrey R.
Other Authors: Univ Arizona, Dept Med
Language:en
Published: Public Library of Science 2016
Online Access:http://hdl.handle.net/10150/621276
http://arizona.openrepository.com/arizona/handle/10150/621276