Estimating time since infection in early homogeneous HIV-1 samples using a poisson model
BACKGROUND:The occurrence of a genetic bottleneck in HIV sexual or mother-to-infant transmission has been well documented. This results in a majority of new infections being homogeneous, i.e., initiated by a single genetic strain. Early after infection, prior to the onset of the host immune response...
Main Authors: | Giorgi, Elena, Funkhouser, Bob, Athreya, Gayathri, Perelson, Alan, Korber, Bette, Bhattacharya, Tanmoy |
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Other Authors: | Los Alamos National Laboratory, Los Alamos, NM 87545, USA |
Language: | en |
Published: |
BioMed Central
2010
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Online Access: | Giorgi et al. BMC Bioinformatics 2010, 11:532 http://www.biomedcentral.com/1471-2105/11/532 http://hdl.handle.net/10150/610176 http://arizona.openrepository.com/arizona/handle/10150/610176 |
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