Estimating time since infection in early homogeneous HIV-1 samples using a poisson model

BACKGROUND:The occurrence of a genetic bottleneck in HIV sexual or mother-to-infant transmission has been well documented. This results in a majority of new infections being homogeneous, i.e., initiated by a single genetic strain. Early after infection, prior to the onset of the host immune response...

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Bibliographic Details
Main Authors: Giorgi, Elena, Funkhouser, Bob, Athreya, Gayathri, Perelson, Alan, Korber, Bette, Bhattacharya, Tanmoy
Other Authors: Los Alamos National Laboratory, Los Alamos, NM 87545, USA
Language:en
Published: BioMed Central 2010
Online Access:Giorgi et al. BMC Bioinformatics 2010, 11:532 http://www.biomedcentral.com/1471-2105/11/532
http://hdl.handle.net/10150/610176
http://arizona.openrepository.com/arizona/handle/10150/610176