Peroxynitrite formation and sinusoidal endothelial cell injury during acetaminophen-induced hepatotoxicity in mice

Peroxynitrite formation and sinusoidal endothelial cell injury during acetaminophen-induced hepatotoxicity in mice

INTRODUCTION:Vascular injury and accumulation of red blood cells in the space of Disse (hemorrhage) is a characteristic feature of acetaminophen hepatotoxicity. However, the mechanism of nonparenchymal cell injury is unclear. Therefore, the objective was to investigate if either Kupffer cells or int...

Full description

Bibliographic Details
Main Authors: Knight, Tamara, Jaeschke, Hartmut
Other Authors: Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
Language:en
Published: BioMed Central 2004
Online Access:Comparative Hepatology 2004, 3(Suppl 1):S46 http://www.comparative-hepatology.com/content/3/S1/S46
http://hdl.handle.net/10150/610125
http://arizona.openrepository.com/arizona/handle/10150/610125

Internet

Comparative Hepatology 2004, 3(Suppl 1):S46 http://www.comparative-hepatology.com/content/3/S1/S46
http://hdl.handle.net/10150/610125
http://arizona.openrepository.com/arizona/handle/10150/610125

Similar Items