Phospholipase D promotes Arcanobacterium haemolyticum adhesion via lipid raft remodeling and host cell death following bacterial invasion
BACKGROUND:Arcanobacterium haemolyticum is an emerging bacterial pathogen, causing pharyngitis and more invasive infections. This organism expresses an unusual phospholipase D (PLD), which we propose promotes bacterial pathogenesis through its action on host cell membranes. The pld gene is found on...
Main Authors: | Lucas, Erynn, Billington, Stephen, Carlson, Petteri, McGee, David, Jost, B. H. |
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Other Authors: | Department of Veterinary Science and Microbiology, The University of Arizona, 1117 E Lowell Street, Tucson, AZ 85721, USA |
Language: | en |
Published: |
BioMed Central
2010
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Online Access: | Lucas et al. BMC Microbiology 2010, 10:270 http://www.biomedcentral.com/1471-2180/10/270 http://hdl.handle.net/10150/610055 http://arizona.openrepository.com/arizona/handle/10150/610055 |
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