Phospholipase D promotes Arcanobacterium haemolyticum adhesion via lipid raft remodeling and host cell death following bacterial invasion

BACKGROUND:Arcanobacterium haemolyticum is an emerging bacterial pathogen, causing pharyngitis and more invasive infections. This organism expresses an unusual phospholipase D (PLD), which we propose promotes bacterial pathogenesis through its action on host cell membranes. The pld gene is found on...

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Bibliographic Details
Main Authors: Lucas, Erynn, Billington, Stephen, Carlson, Petteri, McGee, David, Jost, B. H.
Other Authors: Department of Veterinary Science and Microbiology, The University of Arizona, 1117 E Lowell Street, Tucson, AZ 85721, USA
Language:en
Published: BioMed Central 2010
Online Access:Lucas et al. BMC Microbiology 2010, 10:270 http://www.biomedcentral.com/1471-2180/10/270
http://hdl.handle.net/10150/610055
http://arizona.openrepository.com/arizona/handle/10150/610055